Are Microbes Causing Autoimmune Conditions?
When I rant about how diet can cure autoimmune conditions I am sure that I sound kind of out there. It is an outrageous theory. To say that a whole series of ailments from autoimmune arthritis to obesity to autism can be stopped or reversed by a combination of antibiotics, antifungals, changes in diet, and microbiota sounds strange. You must be wondering WHERE on Earth I am getting this bizarre theory and what sort of evidence I can possibly have that all of these conditions are related. I am glad you asked. This area of scientific knowledge is growing rapidly. So rapidly that this current (June 2014) article is actually a summary of what scientists already know. http://www.ncbi.nlm.nih.gov/pubmed/24882755 If you want to read more about it, or understand all the mathematical modeling necessary to allow us to develop solutions to the scary side effects of dysbiosis, the following article has a pretty readable abstract indicating how few genes mammals have and how much we rely on our microbes to define our immunity, our metabolism and our reaction to pathogens. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000997/ This article is from the journal Lupus published May 2014. http://www.ncbi.nlm.nih.gov/pubmed/24763536 This is from the Brief of Functional Genomics about the microbes most likely to be impacting type 2 diabetes and obesity http://www.ncbi.nlm.nih.gov/pubmed/23616309 A more complete analysis of gut flora and obesity http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754967/ There is an interesting sentence here...
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